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701
:
90 minutes, determined as set forth under Uncoated Tablets.
791:
between 5.0 and 7.5, in a solution prepared by dissolving 1 Lozenge in 100 mL of water at 37
and allowing the solution to cool to room temperature.
467:
meet the requirements.
81, blending not less than 5 Lozenges for 18 to 20 minutes in a high-speed blender jar containing 100.0 mL of water. Add 400.0 mL of dimethylformamide, and blend for an additional 10 minutes. Dilute an accurately measured volume of this solution quantitatively with a mixture of dimethylformamide and water (4:1) to obtain a stock solution containing about 400 USP Nystatin Units per mL. Dilute an accurately measured volume of this stock solution quantitatively with Buffer No. 6 to obtain a Test Dilution having a nystatin concentration assumed to be equal to the median dose level of the Standard. [NOTE—The Test Dilution of the specimen and the test dilutions of the Standard contain the same amount of dimethylformamide (about 4%).]