C10H12O 148.21

Benzene, 1-methoxy-4-(1-propenyl)-, (E)-.
(E)-p-Propenylanisole [4180-23-8].

Synthetic [104-46-1].

Packaging and storage— Preserve in tight, light-resistant containers.

Labeling— Label it to indicate whether it is obtained from natural sources or is prepared synthetically.

Specific gravity 841: between 0.983 and 0.988.

Congealing temperature 651: not lower than 20.

Distilling range, Method I 721: between 231 and 237, a correction factor of 0.063 per mm being applied as necessary.

Angular rotation 781A: between 0.15 and +0.15.

Refractive index 831: between 1.557 and 1.561.

Heavy metals, Method II 231: 20 µg per g.

Aldehydes and ketones— Shake 10 mL with 50 mL of a saturated solution of sodium bisulfite in a graduated cylinder, and allow the mixture to stand for 6 hours: no appreciable diminution in the volume of Anethole occurs, and no crystalline deposit separates.

Limit of phenols— Shake 1 mL with 20 mL of water, and allow the liquids to separate. Pass the water layer through a filter paper previously moistened with water, and to 10 mL of the filtrate add 3 drops of ferric chloride TS: no purple or purplish color is produced.

Organic volatile impurities, Method V 467: meets the requirements.

Residual solvents 467: meets the requirements.

Expert Committee : (EM105) Excipient Monographs 1

USP29–NF24 Page 3275

Phone Number : 1-301-816-8262